Drug Discovery and Evaluation: Safety and Pharmacokinetic Assays free ebook download.

Home : Book details

Drug Discovery and Evaluation: Safety and Pharmacokinetic Assays free ebook download

Category:
Chemistry

Views: 74
Likes: 1

Catalogue

Author(s):	Franz J. Hock

Date:	2024	Format:	pdf	Language:	English	ISBN/ASIN:	3031355288
Pages:	2810	OCR:		Quality:		ISBN13:
Uploader:	gestalt	Upload Date:	10/30/2024 8:59:38 PM

To download click on link in the Links Table below

Description: Click to see full description

3031355288 pdf
Many aspects of drug safety have become an outstanding and even persistent issue and may occur during the process of both drug discovery and development. Until 15 years ago, drug discovery and evaluation was primarily a sequential process starting with the selection of the most pharmacologically active compound from a series of newly synthesized small molecule chemical series by means of distinctive pharmacological assays. Safety aspects were addressed by evaluation of the selected compound at high doses in a series of specific studies directed at indications other than the intended indication of the new compound. These tests are then followed by pharmacokinetic studies, which are primarily conducted to confirm whether the selected compound possesses a suitable half-life for sufficient exposure and efficacy and, whether it has the desired properties specificity to the intended route of administration. Safety aspects relied predominantly on the conduct of single and repeat toxicologydose studies, which inform changes in organ structure rather than organ function. Both toxicological and pharmacokinetic studies are adapted to the progress of studies in clinical pharmacology and clinical trials. The new edition of this well and broadly accepted reference work contains several innovative and distinguished chapters.

Links Table

	Title	Link	Password	Size (MB)	Thank to	Inform Admin
3275062	Book	https://nitroflare.com/view/9ABB349392ED...		0.00	gestalt

Tags: Assays Discovery Drug Evaluation Pharmacokinetic Safety

Title	Link	Password	Size	Reason

Those who downloaded this book also downloaded the following books:
Comments

New comment: